Allele/Variant

Trp53tm1.1Wgu

Species
Mus musculus
Symbol
Trp53tm1.1Wgu
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53K117R
Description
Exon 4 was replaced with a modified exon 4 in which nucleotide substitutions (AG-to-GA) result in the amino acid substitution of lysine with arginine at position 117 (p.K117R). A loxP site flanked neomycin resistance gene cassette inserted downstream of the modified exon 4 was removed by Cre-mediated recombination.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations