Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Mpz/GJB1-Prx*)#Brp
MGI:5431952Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Mpz/GJB1-Prx*)#Brp

Species
Mus musculus
Symbol
Tg(Mpz/GJB1-Prx*)#Brp
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • PrxdeltaTg
Description
The rat Mpz promoter was fused to the human GJB1 promoter to achieve Schwann cell-specific expression of the mouse cDNA lacking the sequence encoding amino acids 130 to 199 (the Drp2 binding site). An N-terminal FLAG tag was added to the mouse cDNA. The pound symbol (#) is used when no line is specified and or lines are pooled.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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