Cep290^b2b1454Clo

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Species

Mus musculus

Symbol

Cep290^b2b1454Clo

Category

allele

Allele of gene

Cep290

Transgenic Constructs

None

Synonyms

• Cep290^c.T4670A
• Checkers

Description

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to A substitution at coding nucleotide 4670 in exon 34 of the cDNA (c.4670T>A, NM_146009). This changes the leucine residue to a translation stop at position 1557 of the encoded protein (p.L1557*).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations