Kdm6a^{tm1a(EUCOMM)Jhha}

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Species

Mus musculus

Symbol

Kdm6a^{tm1a(EUCOMM)Jhha}

Category

allele

Allele of gene

Kdm6a

Transgenic Constructs

None

Synonyms

• Utx^flox

Description

The targeting vector from EUCOMM was used to insert an FRT flanked lacZ and neo cassette and a loxP site upstream of exon 3 and a second loxP site downstream of exon 3 via homologous recombination. Slightly reduced levels of mRNA expression are seen in hemizygous male embryonic stem cells carrying this allele indicating that this is a hypomorphic allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations