Allele/Variant

Raf1tm2.1Ara

Species
Mus musculus
Symbol
Raf1tm2.1Ara
Category
allele
Allele of gene
Raf1
Transgenic Constructs
None
Synonyms
  • Raf1D486N
Description
A targeting vector containing a loxP site, cDNA spanning exons 13 through 16, neo cassette, second loxP site and modified exon 13 was inserted into intron 12. The modified exon 13 contains nucleotide substitution(s) that result in the amino acid substitution of asparagine for aspartic acid at position 486 (D486N). Cre-mediated recombination removed the cDNA and neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
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