Allele/Variant

Rasa1tm1Wid

Species
Mus musculus
Symbol
Rasa1tm1Wid
Category
allele
Allele of gene
Rasa1
Transgenic Constructs
None
Synonyms
  • RasGAPD455A
Description
Exon 10 was replaced with a modified one in which nucleotide substitutions (GAT GGG to GCC GGC) results in the amino acid substitution of alanine for aspartic acid at position 455 (D455A). This modification is predicted to produce a caspase-resistant protein. A floxed neo cassette was inserted downstream of the modified exon 10.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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