Version: 8.0.0
Date: Tue Jan 28 2025
Nrastm1.1Emfu
MGI:5447943
Allele of Nras
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Nrastm1.1Emfu

Species
Mus musculus
Symbol
Nrastm1.1Emfu
Category
allele
Allele of gene
Nras
Transgenic Constructs
None
Synonyms
  • LTR
  • LTR9NS
Description
A floxed PGk/Tn4 neo cassette and the Akv1-99 murine leukemia virus long terminal repeat were inserted into intron 1 via homologous recombination. The viral long terminal repeat was inserted at the proviral integration site before nucleotide 1062 of the GenBank sequence no. L19607. Cre mediated recombination removed the neo cassette. Q-RT-PCR analysis indicated increased mRNA expression in most tissues in heterozygous and homozygous mice. Western blot analysis confirmed increased protein expression.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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