Allele/Variant

Tg(SOD1*G85R)#Roos

Species
Mus musculus
Symbol
Tg(SOD1*G85R)#Roos
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • G85R
Description
This transgene consists of the human SOD1 carrying a glycine to arginine substitution at amino acid 85 (G86R), a mutation associated with familial amyotrophic lateral sclerosis. In addition, loxP sites were engineered to flank the G86R sequence. The pound symbol (#) is used when line is not specified and/or lines are pooled.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations