Allele/Variant

Tg(Acta2-cre/ERT2)1Ikal

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

alphaSMACreERT2

Description

The cre/ERT2 cDNA and BGH polyA cDNAs was inserted into a construct containing the vascular smooth muscle alpha-actin (Acta2) promoter. Functionality of the construct to modify floxed reporter constructs was tested by transient transfection of smooth muscle cell cultures. The purified vector was injected into fertilized C57BL/6 oocytes.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

Acta2

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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