Version: 8.0.0
Date: Tue Jan 28 2025
Hdctm1.1(icre)Wwis
MGI:5461698
Allele of Hdc
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Hdctm1.1(icre)Wwis

Species
Mus musculus
Symbol
Hdctm1.1(icre)Wwis
Category
allele
Allele of gene
Hdc
Transgenic Constructs
Synonyms
  • HDC-Cre
Description
A targeting vector was generated to insert an improved IRES2i site, a humanized cre open reading frame and an FRT-flanked neo selection cassette into exon 12 of histidine decarboxylase between the stop codon and polyadenylation sequence, by homologous recombination in ES cells. Chimeras were produced by ES cell injection into C57BL/6J blastocysts. The resulting line was bred with Flp deleter mice to remove the neo cassette.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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