Stk39^tm1.1Arte

---

Species

Mus musculus

Symbol

Stk39^tm1.1Arte

Category

allele

Allele of gene

Stk39

Transgenic Constructs

None

Synonyms

• SPAK^243A

Description

Exon 6 was replaced with an FRT-flanked neo cassette and a modified exon 6 in which an A to G transition results in the amino acid substitution of alanine for threonine at position 243 (T243A). This mutation is designed to prevent activation by WNK isoforms. Flp-mediated recombination removed the neo cassette.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations