Allele/Variant

Tg(APOE-FGF23*R176Q)#Ack

Species
Mus musculus
Symbol
Tg(APOE-FGF23*R176Q)#Ack
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • FGF23-TG
Description
This transgene consists of the human APOE promoter with exon 1 and part of exon 2 and the human FGF23 cDNA with the R176Q mutation tagged with a myc epitope followed by the APOE poly(A) and hepatic control region. The APOE promoter drives expression of FGF23 in the liver. Two lines were established however, the pound symbol (#) is used because the line is not specified and lines are pooled.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations