Version: 8.0.0
Date: Tue Jan 28 2025
Cd247tm2.1Lov
MGI:5468025
Allele of Cd247
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cd247tm2.1Lov

Species
Mus musculus
Symbol
Cd247tm2.1Lov
Category
allele
Allele of gene
Cd247
Transgenic Constructs
None
Synonyms
  • TCRzeta6F
Description
Exons 3 through 8 were replaced with the corresponding wild-type sequence with a C-terminal FLAG tag (6Y-FLAG), an FRT-flanked neo cassette, a loxP site and the corresponding sequence in which the six immunoreceptor tyrosine-based activation motif (ITAM) tyorsines mutated to encode phenylalanine followed by a C-terminal Myc tag (6F-Myc). Cre-mediated recombination removed the 6Y-FLAG tag and neo cassette. The 6F-Myc tag remains intact.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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