Version: 8.0.0
Date: Tue Jan 28 2025
Tg(CD68-icre)1Bwlx
MGI:5474196Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(CD68-icre)1Bwlx

Species
Mus musculus
Symbol
Tg(CD68-icre)1Bwlx
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CD68:cre
Description
A 2.9 kb fragment of the 5' flanking sequence and the 83-bp first intron of the human CD68 gene was cloned into a vector in front of codon-improved cre and polyadenylation sequences. 2 founder lines were selected for analysis, based on expression levels in isolated peritoneal F4/80+ cells. One line expressed cre in sperm and egg cells so the other line was used for further studies.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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