Allele/Variant

Cers1tm1.1Kwi

Species
Mus musculus
Symbol
Cers1tm1.1Kwi
Category
allele
Allele of gene
Cers1
Transgenic Constructs
None
Synonyms
None
Description
Exon 1 was replaced with a modified exon 1 lacking the translation initation site. An FRT-flanked neo cassette was inserted upstream of exon 2. An EGFP gene with a splice acceptor and splice donor replaced part of exon 3 with additional translation reinitiation sites. Flp-mediated recombination removed the neo cassette. Western blot analysis confirmed the absence of protein expression in the forebrain, cerebellum, spinal cord and muscle and presence of Gdf1 protein expression in E10 embryos. No GFP expression is detected by western blot analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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