Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh
MGI:5476442Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh

Species
Mus musculus
Symbol
Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CD11c.LuciDTR
Description
A cDNA construct encoding EGFP, cre recombinase, human diphtheria toxin receptor (DTR; HBEGF) and click beetle green 99 (CBG99) luciferase was generated, with coding sequences separated by self-cleaving 2A viral sequences. The presence of 2A sequences results in stoichiometric translation of the individual proteins. This construct was inserted at the ATG start codon of Itgax in the RPCI-24-7812 bacterial artificial chromosome by recombineering in bacterial cells. The modified BAC was linearized and injected into pronuclei of fertilized C57BL/6N oocytes and line 2 was established.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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