Allele/Variant

Gt(ROSA)26Sortm5.1(Smad7-CFP)Mgn

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm5.1(Smad7-CFP)Mgn
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
None
Synonyms
  • -60/IRBEA4-TA-CFP
Description
This allele was created by RMCE in Gt(ROSA)26Sortm1Mgn. The original selections cassettes (puromycin N-acetyltransferase and a truncated form of HSV1 thymidine kinase and EM7-driven neomycin resistance) were replaced by a cassette composed of ROSA26 upstream sequence deleted from the start codon to -60, a 4X multimer of the IBRE element from the Smad7 gene controlling expression of the CFP reporter. An upstream FLP flanked hygromycin selection cassette was subsequently removed by flp recombinase.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations