Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm1(creB)Dwi
MGI:5486456
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm1(creB)Dwi

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm1(creB)Dwi
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • Rosa26-creB
Description
A cassette was constructed with the creB fragment of cre recombinase (codons 60-343) fused to an FKBP dimerization domain by an F2 linker and included a polyadenylation sequence. This cassette was cloned into a plasmid containing Gt(ROSA)26Sor homology sequences. The linearized plasmid was introduced into ES cells and by homologous recombination the creB sequence was inserted into the Gt(ROSA)26Sor locus. When crossed to mice expressing the creA sequence, the two fragments will dimerize in presence of AP20187 and a functional cre protein will be produced.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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