Allele/Variant

Nrcamtm2e.1(KOMP)Wtsi

Species
Mus musculus
Symbol
Nrcamtm2e.1(KOMP)Wtsi
Category
allele
Allele of gene
Nrcam
Transgenic Constructs
None
Synonyms
None
Description
The L1L2_Bact_P cassette was inserted at position 44596221 of Chromosome 12 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette created a reporter knockout mouse, and subsequent cre expression excised the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations