Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc
MGI:5495288
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • Gt(ROSA)26Sortm2(EWSR1/ATF1)Mrc
Description
A cDNA clone was produced using RNA purified from a confirmed "clear cell sarcoma" tumor. The cDNA contained the EWSR1/ATF1 fusion product of the t(12;22) chromosomal translocation typical of these tumors. This cDNA was inserted downstream of a floxed pgk-neomycin cassette and upstream of an IRES-EGFP. Stop codons in the neomycin cassette prevent EWSR1/ATF1 and EGFP expression.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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