Allele/Variant

Unc5dtm1Kln

Species
Mus musculus
Symbol
Unc5dtm1Kln
Category
allele
Allele of gene
Unc5d
Transgenic Constructs
None
Synonyms
None
Description
An cassette containing an IRES, Mapt and lacZ fusion (Tau-LacZ), and floxed neo cassette replaced the open reading frame in exon 8. The insertion results in a missense mutation in the ectodomain. Western blot analysis confirmed the absence of protein expression in the brain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal axon extension
MGI
abnormal neuronal migration
MGI
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Disease Associations

No data available