Allele/Variant

Gt(ROSA)26Sortm2.1(CAG-PSTPIP1*)Dtg

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm2.1(CAG-PSTPIP1*)Dtg
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • Rosa-26-PSTPIP1 A230TSTOP del
Description
The targeting construct inserted into the locus contained a CAG promoter that drives ubiquitous expression of the human cDNA with nucleotide substitutions that result in the amino acid substitution of threonine for alanine at position 230 (A230T) preceded by a floxed STOP cassette and followed by an IRES and the truncated human CD2 tag. Cre-mediated recombination removed the floxed STOP cassette.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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