Allele/Variant

Gt(ROSA)26Sortm1Fan

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm1Fan
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
None
Synonyms
  • ROSAAC
Description
A cassette containing a CMV/beta-actin promoter/enhancer, a loxP-Neo-3xpA-loxP stop signal, A-CREB, an IRES and a nuclear localized EGFP was inserted into the locus via homologous recombination. Acidic CREB (A-CREB) acts as a highly selective pan-dominant-negative reagent to the CREB gene family and consists of an acidic amphipathic extension fused to the N terminus of the CREB leucine zipper domain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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