Allele/Variant

Rragatm1.1Dmsa

Species
Mus musculus
Symbol
Rragatm1.1Dmsa
Category
allele
Allele of gene
Rraga
Transgenic Constructs
None
Synonyms
  • RagAGTP
  • RagAQ66L
Description
A floxed hygromycin resistance/STOP cassette was inserted upstream of a modified coding exon in which an A to T transversion results in the amino acid substitution of lysine for glutamine at position 66 (Q66L). Cre-mediated recombination removed the hygromycin resistance/STOP cassette. The predicted protein is constitutively active.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations