Sec24c^{tm1d(EUCOMM)Wtsi}

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Species

Mus musculus

Symbol

Sec24c^{tm1d(EUCOMM)Wtsi}

Category

allele

Allele of gene

Sec24c

Transgenic Constructs

None

Synonyms

• Sec24c^-

Description

The L1L2_Pgk_P cassette was inserted at position 20679037 of Chromosome 14 upstream of exon 3. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the PGK promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 3 at position 20679926. A null allele was created by flp and cre recombinase expression in mice, resulting in the deletion of the lacZ sequences, the neomycin selection cassette and exon 3.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations