Allele/Variant

Gt(ROSA)26Sortm11(CAG-Braf*/ERT2)Rkuhn

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm11(CAG-Braf*/ERT2)Rkuhn
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • BRAFV637EERT2
Description
Recombinase mediated cassette exchange involving Gt(ROSA)26Sortm1Rkuhn introduced into the locus a CAG promoter, floxed stop cassette and a fusion of the mouse cDNA containing the amino acid substitution of glutamic acid for valine at position 673 and an N-terminus nuclear export signal to the modified estrogen receptor (ERT2). The mutation is equivalent to the human mutation V600E.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations