Version: 8.0.0
Date: Tue Jan 28 2025
Psaptm4.1Ggb
MGI:5510529
Allele of Psap
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Psaptm4.1Ggb

Species
Mus musculus
Symbol
Psaptm4.1Ggb
Category
allele
Allele of gene
Psap
Transgenic Constructs
None
Synonyms
  • AB-
Description
Nucleotide substitutions result in the amino acid substitution of Cys 4 of saposins A and B located in exon 4 (saposin A domain) and exon 7 (saposin B domain) with phenylalanine. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted upstream of the modified exon 7. Western blot analysis confirmed the absence of saponin A and B, overexpression of saponin C and normal expression of saponin D in the cerebrum and liver.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page