Version: 8.0.0
Date: Tue Jan 28 2025
Pax6tm2(Pax6_i5a,Pax2)Xzh
MGI:5512910
Allele of Pax6
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Pax6tm2(Pax6_i5a,Pax2)Xzh

Species
Mus musculus
Symbol
Pax6tm2(Pax6_i5a,Pax2)Xzh
Category
allele
Allele of gene
Pax6
Transgenic Constructs
Synonyms
  • Pax65a
Description
The coding sequence (exons 4 through 13) was replaced with a loxP site, cDNA encoding an alternatively spliced isoform for Pax6 that contains 14 amino acid inserted within the PD domain that changed its DNA binding specificity (5a), an FRT-flanked neomycin resistance/STOP cassette, loxP site and cDNA encoding Pax2. This allele expressed the 5a isoform of Pax6 (Pax6_i5a).
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
  • Pax2
  • Pax6
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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