Allele/Variant

Tg(Prnp-ATXN3*70Q)70.61Olri

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

None

Description

The mouse prion promoter (containing 1140 bp of the prion protein gene upstream of exon 1, the complete exon 1, intron 1, and the first 52 bp of exon 2) drives the expression of the full-length human ATAXIN-3 (ATAXIN-3c isoform that contains an additional ubiquitin-interacting motif at its C terminus) containing 70 CAG repeats. Four lines were created: 70.42, 70.48, 70.61, and 70.66.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

ATXN3 (Hsa)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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