The transgene contains a CAG promoter driving ubiquitous expression of the human cDNA. Cre-mediated recombination removed a floxed neomycin resistance cassette inserted between the promoter and cDNA. The pound symbol (#) is used when no line is specified and/or lines are pooled. The #a line reflects the cre-recombined transgene while the unrecombined transgene is referred to as line #.