Version: 8.0.0
Date: Tue Jan 28 2025
Itm2atm1.2Buck
MGI:5518653
Allele of Itm2a
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Itm2atm1.2Buck

Species
Mus musculus
Symbol
Itm2atm1.2Buck
Category
allele
Allele of gene
Itm2a
Transgenic Constructs
None
Synonyms
  • Itm2aKO-IRESnacZ
  • Itm2aXKO
Description
A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 4. An IRES-nlacZ was inserted into exon 6. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed exons 2 through 4 floxed but left the lacZ reporter intact. In situ hybridization confirmed reduced transcript expression in E11.5 embryos.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page