Version: 8.0.0
Date: Tue Jan 28 2025
Tnctm1(cre/ERT2)Cmha
MGI:5520052
Allele of Tnc
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tnctm1(cre/ERT2)Cmha

Species
Mus musculus
Symbol
Tnctm1(cre/ERT2)Cmha
Category
allele
Allele of gene
Tnc
Transgenic Constructs
Synonyms
  • Tenascin-C-CreER2
  • TncYFP-CreER
Description
Using homologous recombination, a cre/ERT2-IRES-EGFP cassette was inserted immediately upstream of the translation start ATG codon in exon 2 of the tenascin C gene. A neo selection marker flanked by frt sites followed the cre cassette. EGFP expression is similar to endogenous Tnc expression in the kidney inner medulla interstitial cells. No significant cre-dependent reporter activity is observed in absence of tamoxifen treatment.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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