Allele/Variant

Tg(TG-BRAF*V600E)3Jaf

Species
Mus musculus
Symbol
Tg(TG-BRAF*V600E)3Jaf
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Tg-BRAF3
Description
The human BRAF cDNA with a thymine-to-adenine transversion at position 1799A leading to a valine-to-glutamate substitution at residue 600 (V600E) and an NH2-terminal myc tag are under the control of the thyroid-specific bovine thyroglobulin promoter. Quantitative RT-PCR and Western blot analysis confirmed mRNA and protein expression in thyroid tissue. This is the lower expressing line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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