Allele/Variant

Tg(Ccl19-cre)489Biat

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

Ccl19-Cre
transgene insertion 489, Thomas Ruelicke

Description

A truncated human CD4-IRES-cre sequence with a stop codon was inserted into exon 1 of Ccl19 at the ATG translational start codon in a BAC (RP23446D10). Ccl21b, which is located very close to Ccl19 in the BAC, was disrupted by inserting the human CD8 gene into the first exon. Seven founders were generated and screened by crossing to R26-EYFP reporter mice. 2 of 7 lines had identical stromal-cell specific transgene expression, and founder line 1 was used for all subsequent studies.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

Ccl19 (Mmu)

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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