Version: 8.0.0
Date: Tue Jan 28 2025
Tnfaip3tm3.1Ama
MGI:5528684
Allele of Tnfaip3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tnfaip3tm3.1Ama

Species
Mus musculus
Symbol
Tnfaip3tm3.1Ama
Category
allele
Allele of gene
Tnfaip3
Transgenic Constructs
None
Synonyms
  • Tnfaip3OTU
Description
A floxed neomycin resistance cassette was inserted upstream of exon 3. Exon 3 was replaced with one in which a nucleotide substitution(s) results(s) in the amino acid substitution of alanine for cysteine at position 103 (C103A). This mutation disrupts the deubiquitinating function of the OTU domain. Cre-mediated recombination removed the neomycin resistance cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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