Cfb^{tm1.1(KOMP)Wtsi}

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Species

Mus musculus

Symbol

Cfb^{tm1.1(KOMP)Wtsi}

Category

allele

Allele of gene

Cfb

Transgenic Constructs

None

Synonyms

None

Description

The insertion of the L1L2_Bact_P cassette created a deletion of size 3607 starting at position 35076626 and ending at position 35080233 of Chromosome 17 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site was followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site, and subsequent Cre-mediated excision removed the neomycin selection cassette.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations