Allele/Variant

Tfap2atm1.1Hsv

Species
Mus musculus
Symbol
Tfap2atm1.1Hsv
Category
allele
Allele of gene
Tfap2a
Transgenic Constructs
None
Synonyms
  • AP-2aki
Description
An IRES, lacZ and floxed neomycin resistance cassette were inserted into exon 7 via homologous recombination resulting in disruption of the DNA binding domain. Cre-mediated recombination removed the floxed neo cassette. The mutant transcript encodes the first 6 exons of the gene followed by the IRES-lacZ message. The pattern of lacZ expression in mutant animals is similar to that of the endogenous protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations