Allele/Variant

Cyp11b2tm1.1(cre)Brlt

Species
Mus musculus
Symbol
Cyp11b2tm1.1(cre)Brlt
Category
allele
Allele of gene
Cyp11b2
Transgenic Constructs
Synonyms
  • ASCre
Description
A targeting construct with cre recombinase and an Frt-flanked neo cassette was inserted by homologous recombination into the Cyp11b2 (aldosterone synthase, AS) locus, replacing most of the coding region, retaining only exon 1, intron 1 and the first part of exon 2. Germline animals were crossed to Flpe deleter mice to remove the neo cassette. Mice homozygous for the allele are effectrively null for Cyp11b2 function.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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