Allele/Variant

Tgfbr2tm1.1Hcd

Species
Mus musculus
Symbol
Tgfbr2tm1.1Hcd
Category
allele
Allele of gene
Tgfbr2
Transgenic Constructs
None
Synonyms
  • Tgfbr2G357W
Description
Site-directed mutagenesis was performed to substitute glycine 358 with tryptophan (GGC->TGG; guanine to thymine and cytosine to guanine at nucleotides 1069 and 1071 respectively) in exon 4 of the targeted gene. A loxP-flanked neomycin selection cassette was placed in intron 3. Cre-mediated recombination removed the floxed neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations