Allele/Variant

H2-Ab1b-tm1Wug

Species
Mus musculus
Symbol
H2-Ab1b-tm1Wug
Category
allele
Allele of gene
H2-Ab1
Transgenic Constructs
None
Synonyms
  • H2-Ab1tm1Wug
  • IAbetabstopf
Description
A floxed neomycin resistance/STOP cassette was inserted into intron 1. Flow cytometry confirmed the absence of protein expression in the peripheral blood, spleen and bone marrow.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal B cell physiologyMGI
abnormal dendritic cell physiologyMGI
absent CD4-positive, alpha-beta T cells
MGI
decreased susceptibility to experimental autoimmune encephalomyelitisMGI
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Disease Associations

No data available