Allele/Variant

Tg(Thy1-VAPB*P56S,-EGFP)D3Cai

Species
Mus musculus
Symbol
Tg(Thy1-VAPB*P56S,-EGFP)D3Cai
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • P56S VAPB Tg
Description
The human VAPB cDNA with a substitution of proline with serine at residue 56 (P56S) is under the control of a pan-neuronal promoter Thy1.2. Three lines were generated. qRT-PCR indicated more than 20-fold overexpression of mRNA. Protein expression was detected in the cerebral cortex, spinal cord, striatum, and hippocampus.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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