Allele/Variant

Vangl2tm2.2Mdea

Species
Mus musculus
Symbol
Vangl2tm2.2Mdea
Category
allele
Allele of gene
Vangl2
Transgenic Constructs
None
Synonyms
  • Vangl2deltaATG
Description
A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the resistance cassette. Cre-mediated recombination removed exons 2 and 3. Western blot analysis confirmed the absence of protein expression in the brain at E18.5.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations