Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Prnp-APPSweArc)#Rmni
MGI:5553464Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Prnp-APPSweArc)#Rmni

Species
Mus musculus
Symbol
Tg(Prnp-APPSweArc)#Rmni
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • arcABeta
Description
The human APP695 containing the Swedish K670N and M671L and Artic E693G mutations is under the control of the prion protein promoter. The pound symbol (#) is used because the line is not specified, although the line used has a 6-fold overexpression of APP compared to endogenous APP levels.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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