Kit^{tm2.1(cre/Esr1*)Jmol}

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Species

Mus musculus

Symbol

Kit^{tm2.1(cre/Esr1*)Jmol}

Category

allele

Allele of gene

Kit

Transgenic Constructs

Synonyms

• Kit^MCM
• Kit^MerCreMer

Description

A cDNA encoding MerCreMer (cre recombinase fused to two modified estrogen receptor ligand binding domains at both ends), and an frt-flanked neomycin selection cassette were cloned in-frame with the Kit ATG start site. Homologous recombination was performed in ES cells, and chimeras were bred to flp-expressing knock-in mice to delete the selection marker.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations