Version: 8.0.0
Date: Tue Jan 28 2025
Lmnatm1.2Yxz
MGI:5575530
Allele of Lmna
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Lmnatm1.2Yxz

Species
Mus musculus
Symbol
Lmnatm1.2Yxz
Category
allele
Allele of gene
Lmna
Transgenic Constructs
None
Synonyms
  • Lmnadelta
Description
A loxP site was inserted upstream of exon 2. An FRT-flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2. Immunofluorescence confirmed the absence of lamin A and C in mouse embryonic fibroblasts.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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