Allele/Variant

Tg(Thy1-FUS*)19Vlb

Species
Mus musculus
Symbol
Tg(Thy1-FUS*)19Vlb
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • FUS-TG
Description
This transgene consists of a fragment of human FUS 1-359 cDNA including 9 bp of 5'-UTR under the control of the Thy1 promoter. This FUS variant is predominantly cytoplasmic as it lacks the nuclear localization signal, highly aggregate-prone, and lacks a region responsible for RNA recognition and binding. Western blot confirmed expression in neural tissues.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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