Allele/Variant

Rcor1tm2.2Gman

Species
Mus musculus
Symbol
Rcor1tm2.2Gman
Category
allele
Allele of gene
Rcor1
Transgenic Constructs
None
Synonyms
None
Description
A loxP site was introduced to intron 3 and an FRT-PGK-Neo-pA-splice donor-FRT-loxP cassette was placed in intron 4. Flpe-mediated recombination removed the FRT-flanked neo cassette leaving loxP sites on either side of exon 4. Cre-mediated recombination removed exon 4 and introduced a premature stop codon. Western blot analysis demonstrated that no detectable protein was present in homozygous E13.5 embryos.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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