Allele/Variant

Ido2tm1.2Gcp

Species
Mus musculus
Symbol
Ido2tm1.2Gcp
Category
allele
Allele of gene
Ido2
Transgenic Constructs
None
Synonyms
None
Description
A loxP site was inserted into exon 9. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted into exon 10. Flp-mediated recombination removed the selection cassette. The insertion of loxP sites in exons 9 and 10 inserted stop codons resulting in a null allele. Cre-mediated recombination removed exons 9 and 10. Western blot analysis confirmed the absence of protein expression in the liver and kidney.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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