Ido2^tm1.2Gcp

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Species

Mus musculus

Symbol

Ido2^tm1.2Gcp

Category

allele

Allele of gene

Ido2

Transgenic Constructs

None

Synonyms

None

Description

A loxP site was inserted into exon 9. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted into exon 10. Flp-mediated recombination removed the selection cassette. The insertion of loxP sites in exons 9 and 10 inserted stop codons resulting in a null allele. Cre-mediated recombination removed exons 9 and 10. Western blot analysis confirmed the absence of protein expression in the liver and kidney.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations