Allele/Variant

Hsbp1tm1Miv

Species
Mus musculus
Symbol
Hsbp1tm1Miv
Category
allele
Allele of gene
Hsbp1
Transgenic Constructs
None
Synonyms
None
Description
A portion of exon 1 following the ATG codon, exon 2, and intron 1 were replaced with a cassette containing an EGFP reporter gene, the thymidine kinase promoter with a simian virus 40 polyA signal and a PGK-neomycin gene flanked by two loxP sites, creating an out-of-frame deletion. Western blot confirmed absence of protein expression. EGFP expression is driven by the Hsbp1 promoter and is detected at E0.5 and E1.5 in blastocysts and during later stages (E8.5-10.5) in heterozygotes.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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