Abcg8^tm1.1Hobb

---

Species

Mus musculus

Symbol

Abcg8^tm1.1Hobb

Category

allele

Allele of gene

Abcg8

Transgenic Constructs

None

Synonyms

None

Description

The Abcg5 and Abcg8 genes are in a head to head orientation. A loxP site and FRT-flanked neomycin cassette were introduced into intron 2 of the Abcg5 gene, and a loxP site was placed in intron 1 of the Abcg8 gene, generating a second allele, Abcg5^tm1.1Hobb. Flpe-mediated recombination removed the FRT-flanked neomycin cassette.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations